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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma

Composition :

MIDODRINE-10MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIHYPOTENSIVES

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - MID0073

Author Details

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FAQs

Midorise 10 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Do not stop taking Midorise 10 Tab on your own. Depending on your medical condition, you are advised to take Midorise 10 Tab for as long as your doctor has prescribed it for you. Do not hesitate to speak with your doctor if you experience difficulty while taking Midorise 10 Tab .

Do not take Midorise 10 Tab if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Midorise 10 Tab only if the benefits outweigh the risks.

Midorise 10 Tab is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Midorise 10 Tab is metabolised to desglymidodrine, an active metabolite that activates alpha-1-adrenergic receptors on arterioles and venules, causing smooth muscle contraction and blood pressure increase. Midodrine may cause a drop in heart rate due to the vagal reflex.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Consuming alcohol along with Midorise 10 Tab is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Midorise 10 Tab in breastfeeding/nursing mothers.

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Driving

Caution

Patients who experience dizziness or lightheadedness while receiving Midodrine should refrain from operating machinery.

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Liver

Caution

Limited information is available on the use of Midorise 10 Tab in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Kidney

Caution

Limited information is available on the use of Midorise 10 Tab in patients with Kidney disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Children

Unsafe

Midorise 10 Tab is not recommended for children below 18 years of age.

About Midorise 10 Tab

Midorise 10 Tab belongs to a category of medications called ‘Antihypotensives’ primarily used to treat hypotension (low blood pressure). Hypotension is when blood pressure drops below the normal range, reducing cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and risk of injury from falls.

Midorise 10 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Take Midorise 10 Tab as prescribed by your doctor. Depending on your medical condition, you are advised to take Midorise 10 Tab for as long as your doctor prescribes it. Some people may experience Supine hypertension, Reflex bradycardia, Arrhythmias, Rash, Nausea, Vomiting, Dyspepsia, Headache, and Urinary retention. Most of these side effects of Midorise 10 Tab do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Midorise 10 Tab or other medicines. If you are a pregnant woman or nursing mother, do not consume Midorise 10 Tab without first consulting your doctor. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Uses of Midorise 10 Tab

Idiopathic postural hypotension or hypotension

Medicinal Benefits Mweb

Medicinal Benefits

Midorise 10 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Midorise 10 Tab

  • Supine hypertension
  • Chest pain
  • Palpitations
  • Headache
  • Blurred vision
  • Reflex bradycardia
  • Arrhythmias
  • Rash
  • Nausea
  • Vomiting
  • Dyspepsia
  • Urinary retention

Drug Warnings

If you are known to be allergic to Midorise 10 Tab or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. If you get pregnant during treatment with Midodrine, you must stop the treatment immediately once the pregnancy is confirmed. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
MidodrineIobenguane (131i)
Severe

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
How does the drug interact with Midorise 10 Tablet:
Coadministration of Dihydroergotamine with Midorise 10 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Dihydroergotamine with Midorise 10 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any of these symptoms like headaches, abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, eye redness, confusion, or slurred speech, consult a doctor right away. Do not discontinue any medications without consulting a doctor.
MidodrineIobenguane (131i)
Severe
How does the drug interact with Midorise 10 Tablet:
Coadministration of Midorise 10 Tablet with Iobenguane can cause a decrease in the absorption of Iobenguane resulting in a low treatment outcomes.

How to manage the interaction:
Co-administration of Midorise 10 Tablet with Iobenguane (131i) can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
MidodrineDoxapram
Severe
How does the drug interact with Midorise 10 Tablet:
Coadministration of Midorise 10 Tablet with doxapram can increase effect of Doxapram.

How to manage the interaction:
Taking Doxapram with Midorise 10 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MidodrineErgotamine
Severe
How does the drug interact with Midorise 10 Tablet:
Using ergotamine together with Midorise 10 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Midorise 10 Tablet and Ergotamine, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Midorise 10 Tablet:
Taking Midorise 10 Tablet along with linezolid could increase the risk or severity of high blood pressure.

How to manage the interaction:
Although taking linezolid with Midorise 10 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
MidodrineMethysergide
Severe
How does the drug interact with Midorise 10 Tablet:
Using methysergide maleate together with Midorise 10 Tablet may cause significant increases in blood pressure.

How to manage the interaction:
Co-administration of Midorise 10 Tablet with Methysergide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • FLUDROCORTISONE
  • METOPROLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Add foods with high vitamin B12, including eggs, fortified cereals, and nutritional yeast, to your daily diet.
  • Salty foods can increase blood pressure. Try eating canned soup, cottage cheese, olives, and pickled items.
  • Drink coffee and caffeinated tea, which may increase blood pressure by stimulating the cardiovascular system.
  • Eat small meals more frequently; large meals may drop in blood pressure as your body works harder to digest larger meals.
  • Drink more water and limit alcohol; dehydration lowers blood pressure.
  • Change body position by standing up slowly.
  • Avoid prolonged bed rest.
  • If you exercise outdoors in extreme heat, take frequent breaks.
  • Avoid spending a long time in saunas, hot tubs, and steam rooms which cause dehydration.

Midorise 10 Tab Substitute

Medicine Composition:

MIDODRINE-10MG

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