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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

LABETALOL-20MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTI- HYPERTENSIVES

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - LA89909

FAQs

Labepure 20mg Injection works by blocking the receptors in the cardiovascular system, this helps in decreasing the blood pressure in the blood vessels. Thereby, helping in lowering the blood pressure to normal.

Postural hypotension could be a side-effect of Labepure 20mg Injection. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.

Labepure 20mg Injection is used to treat severe hypertension of pregnancy (high blood pressure in pregnancy) when the blood pressure needs to be lowered rapidly.

Labepure 20mg Injection may cause erectile dysfunction (impotence). Please consult your doctor if you have any concerns regarding these.

Labepure 20mg Injection might mask the effects of sudden blood loss and might affect pupils during cataract surgery, so inform the surgeon ahead of time that you are on treatment with Labepure 20mg Injection if you are due to have surgery.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is unknown if alcohol affects the results of Labepure 20mg Injection. Please consult your doctor.

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Pregnancy

Caution

Labepure 20mg Injection belongs to pregnancy category C. Your doctor may prescribe Labepure 20mg Injection in case of high blood pressure during pregnancy when rapid control of blood pressure is necessary.

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Breast Feeding

Caution

Small amounts of Labepure 20mg Injection may pass into breastmilk. Please inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Caution

Labepure 20mg Injection may cause dizziness. Hence, do not drive vehicles or operate machines if you fell dizzy after taking Labepure 20mg Injection.

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Liver

Caution

Please inform your doctor if you have liver problems before receiving Labepure 20mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Please inform your doctor if you have kidney problems before receiving Labepure 20mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Labepure 20mg Injection is not recommended for children and adolescents below 18 years.

About Labepure 20mg Injection

Labepure 20mg Injection belongs to the group of anti-hypertensive medicines called beta-blocking agents used to treat severe hypertension (high blood pressure). Additionally, Labepure 20mg Injection is used to control high blood pressure in pregnancy and during anaesthesia. 
 
Labepure 20mg Injection contains ‘labetalol’ that works by blocking the receptors in the cardiovascular (circulatory) system, this helps in decreasing the blood pressure in the blood vessels. Thus, it helps lower the blood pressure to normal.
 
In some cases, Labepure 20mg Injection may cause common side effects such as postural hypotension, dizziness, fatigue, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. Labepure 20mg Injection is not recommended for children below 18 years as efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Labepure 20mg Injection

Hypertension (high blood pressure)

Medicinal Benefits Mweb

Medicinal Benefits

Labepure 20mg Injection belongs to the group of anti-hypertensive medicines called alpha and beta-blocking agents used to treat severe hypertension (high blood pressure). Additionally, Labepure 20mg Injection is used to treat severe hypertension of pregnancy (high blood pressure in pregnancy) and to control blood pressure during anaesthesia. Labepure 20mg Injection contains ‘labetalol’ that works by blocking the receptors in the cardiovascular (circulatory) system, this helps in decreasing the blood pressure in the blood vessels. Thereby, helping in lowering the blood pressure to normal.

Directions for Use

Labepure 20mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Labepure 20mg Injection

  • Postural hypotension
  • Dizziness
  • Fatigue
  • Headache

Drug Warnings

Do not take Labepure 20mg Injection if you are allergic to any of its contents; if you have heart diseases like heart block or sick sinus syndrome (unless you have a pacemaker), heart failure or cardiogenic shock, ongoing low blood pressure, extremely slow heart rate, Prinzmetal angina, asthma or obstructive airway disease, or phaeochromocytoma (tumour of the adrenal gland). Inform your doctor if you have peripheral vascular disease (Raynaud's syndrome or intermittent claudication), diabetes, overactive thyroid, metabolic acidosis, respiratory system problems, heart, kidney or liver problems. Labepure 20mg Injection should not be given to children and adolescents below 18 years.  Consult your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Labepure 20mg Injection:
Co-administration of Labepure 20mg Injection and Salmeterol together can decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labepure 20mg Injection and Salmeterol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not forget to inform the doctor if you have severe chronic obstructive pulmonary disease (COPD) or a history of asthma, as Labepure 20mg Injection is often not advised in these conditions. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Labepure 20mg Injection:
Co-administration of Labepure 20mg Injection and Diltiazem may increase the side effects.

How to manage the interaction:
Although taking Labepure 20mg Injection and Diltiazem together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fatigue, headache, fainting, swelling of hands and legs, breathing difficulty, chest pain, increased or decreased heartbeat, or irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Labepure 20mg Injection:
When Levosalbutamol is used in combination with Labepure 20mg Injection, the therapeutic effectiveness of Levosalbutamol can be decreased which may lead to low treatment outcomes.

How to manage the interaction:
Taking Levosalbutamol with Labepure 20mg Injection may lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Labepure 20mg Injection:
Co-administration of Ceritinib together with Labepure 20mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Labepure 20mg Injection and Ceritinib together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Labepure 20mg Injection:
Taking Labepure 20mg Injection along with Epinephrine can reduce the effects of Epinephrine.

How to manage the interaction:
Taking Labepure 20mg Injection and Epinephrine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LabetalolSaquinavir
Severe
How does the drug interact with Labepure 20mg Injection:
Co-administration of Labepure 20mg Injection along with Saquinavir can increase the risk of irregular heart rhythms.

How to manage the interaction:
Although taking Labepure 20mg Injection and Saquinavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, dizziness, fainting, a slow pulse, or an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Labepure 20mg Injection:
Taking Atazanavir and Labepure 20mg Injection can raise the risk of a possibly serious heart rhythm irregularity.

How to manage the interaction:
Although taking Labepure 20mg Injection and Atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Labepure 20mg Injection:
Co-administration of Labepure 20mg Injection and formoterol together could decrease the effects of both medications.

How to manage the interaction:
Although taking Labepure 20mg Injection and Formoterol together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Labepure 20mg Injection:
Co-administration of Labepure 20mg Injection and Verapamil can increase the risk of side effects.

How to manage the interaction:
Although taking Labepure 20mg Injection and Verapamil together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fatigue, swelling of the extremities, shortness of breath, chest pain, increased or decreased heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
LabetalolDolasetron
Severe
How does the drug interact with Labepure 20mg Injection:
When Dolasetron and Labepure 20mg Injection are taken together, it can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Labepure 20mg Injection and Dolasetron, you can take these medicines together if prescribed by your doctor. However, if you experience sudden dizziness, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SULINDAC
  • INDOMETHACIN
  • VERAPAMIL
  • CLONIDINE
  • DIGOXIN
  • AMIODARONE
  • DISOPYRAMIDE
  • QUINIDINE
  • IMIPRAMINE
  • METFORMIN
  • GLIMEPIRIDE
  • ACARBOSE
  • REPAGLINIDE
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • DONEPEZIL
  • GALANTAMINE
  • RIVASTIGMINE
  • CHLORPROMAZINE

Habit Forming

No

Special Advise

  • Labepure 20mg Injection might interfere with laboratory test results and possibly cause false results such as raised liver function tests. Inform the person doing the tests that you are taking Labepure 20mg Injection.
  • Inform your surgeon ahead of time that you are on treatment with Labepure 20mg Injection if you are due to have any surgery that requires general anaesthesia or cataract surgery.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low fat diet.
  • Regular exercise is also recommended.
  • Eat a diet rich in whole grains, vegetables and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

Labepure 20mg Injection Substitute

Medicine Composition:

LABETALOL-20MG

All Substitutes & Brand Comparisons

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