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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIVIRALS

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (INDIA).
Other Info - VAL0571

Author Details

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FAQs

Valgaciv-450 Tablet 10's contains Valganciclovir that works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.

Valgaciv-450 Tablet 10's may be used to prevent cytomegalovirus infection in patients who received an organ transplant from a donor infected with CMV.

Valgaciv-450 Tablet 10's may cause diarrhoea as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.

Valgaciv-450 Tablet 10's should be used with caution in patients with kidney problems and only in doses as prescribed by a doctor. However, regular blood tests are recommended while taking Valgaciv-450 Tablet 10's to monitor kidney functioning.

You are not recommended to take Valgaciv-450 Tablet 10's with tacrolimus (immunosuppressant) as it may increase the risk of kidney or nerve damage, cause side effects affecting bone marrow function leading to a low number of blood cells. Therefore, please consult a doctor before taking Valgaciv-450 Tablet 10's with other medicines.

Disclaimer

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Alcohol

Caution

The interaction of alcohol with Valgaciv-450 Tablet 10's is unknown. Please consult a doctor before consuming alcohol while using Valgaciv-450 Tablet 10's.

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Pregnancy

Unsafe

Valgaciv-450 Tablet 10's is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Valgaciv-450 Tablet 10's as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness or confusion in some people. Therefore, avoid driving or operating heavy machinery if you experience any of these symptoms after taking Valgaciv-450 Tablet 10's.

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Liver

Caution

Take Valgaciv-450 Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Valgaciv-450 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Valgaciv-450 Tablet 10's should be used in children only if recommended by a doctor.

About Valgaciv-450 Tablet 10's

Valgaciv-450 Tablet 10's belongs to a class of drugs called antivirals used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, Valgaciv-450 Tablet 10's is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV. Cytomegalovirus (CMV) retinitis is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus.

Valgaciv-450 Tablet 10's contains Valganciclovir which works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  

Take Valgaciv-450 Tablet 10's as prescribed by your doctor. You are advised to take Valgaciv-450 Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects of Valgaciv-450 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Valgaciv-450 Tablet 10's or any other medicines, please tell your doctor. Avoid taking Valgaciv-450 Tablet 10's if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Valgaciv-450 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valgaciv-450 Tablet 10's and for 30 days after treatment with Valgaciv-450 Tablet 10's. Drive only if you are alert as Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness, or confusion.

Uses of Valgaciv-450 Tablet 10's

Cytomegalovirus (CMV) infection of the retina

Medicinal Benefits Mweb

Medicinal Benefits

Valgaciv-450 Tablet 10's contains Valganciclovir, an antiviral drug used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Valgaciv-450 Tablet 10's gets converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  Additionally, Valgaciv-450 Tablet 10's is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.

Directions for Use

Take Valgaciv-450 Tablet 10's with food or as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Side Effects of Valgaciv-450 Tablet 10's

  • Diarrhoea
  • Loss of appetite
  • Cough
  • Headache
  • Stomach pain
  • Nausea
  • Fever
  • Tiredness
  • Sinusitis (sinus infection)

Drug Warnings

If you are allergic to Valgaciv-450 Tablet 10's or any other medicines, please tell your doctor. If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valgaciv-450 Tablet 10's. Avoid taking Valgaciv-450 Tablet 10's if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Valgaciv-450 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valgaciv-450 Tablet 10's and 30 days after treatment with Valgaciv-450 Tablet 10's. Men are advised to continue using contraceptive measures for 90 days after treatment with Valgaciv-450 Tablet 10's. Drive only if you are alert as Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness or confusion. If you are having blood dialysis or radiotherapy, please inform your doctor before taking Valgaciv-450 Tablet 10's.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Valgaciv-450 Tablet:
Taking cidofovir with Valgaciv-450 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Valgaciv-450 Tablet with Cidofovir is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valgaciv-450 Tablet:
The combined use of cladribine and Valgaciv-450 Tablet can increase the risk of infections.

How to manage the interaction:
Taking Cladribine with Valgaciv-450 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while urinating - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
ValganciclovirCertolizumab
Severe
How does the drug interact with Valgaciv-450 Tablet:
Taking Valgaciv-450 Tablet and Certolizumab may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Valgaciv-450 Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while urinating - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valgaciv-450 Tablet:
When Valgaciv-450 Tablet is taken with Tenofovir alafenamide it may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenofovir alafenamide and Valgaciv-450 Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
How does the drug interact with Valgaciv-450 Tablet:
Taking Valgaciv-450 Tablet and Deferiprone may increase the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Valgaciv-450 Tablet and Deferiprone, but it can be taken if prescribed by a doctor. If you're having any of these symptoms - like infection, fever, chills, diarrhea, sore throat, trouble breathing, losing weight, or pain while peeing - contact your doctor right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Valgaciv-450 Tablet:
When Valgaciv-450 Tablet is used with Maribavir, it may make Valgaciv-450 Tablet less effective in treating your condition

How to manage the interaction:
Although there is a possible interaction between Valgaciv-450 Tablet and Maribavir, you can take these medicines together if prescribed by your doctor. If you're having any unusual symptoms, contact a doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Valgaciv-450 Tablet:
Taking Clozapine and Valgaciv-450 Tablet may increase the risk of severe infections.

How to manage the interaction:
Taking Clozapine with Valgaciv-450 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valgaciv-450 Tablet:
The combined use of infliximumab and Valgaciv-450 Tablet can increase the risk of infections.

How to manage the interaction:
Co-administration of Valgaciv-450 Tablet with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valgaciv-450 Tablet:
The combined use of etanercept and Valgaciv-450 Tablet can increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Valgaciv-450 Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Valgaciv-450 Tablet:
The combined use of adalimumab and Valgaciv-450 Tablet can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Valgaciv-450 Tablet and Adalimumab, but it can be taken if prescribed by a doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - reach out to your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • ADEFOVIR
  • DIDANOSINE

Habit Forming

No

Special Advise

  • Regular eye tests are recommended if you have a history of cytomegalovirus retinitis to identify issues related to eye health.
  •  If you touch damaged tablets accidentally, wash your hands with soap and water thoroughly. If any powder from tablets gets into your eyes, rinse with sterile or clean water.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.

Valgaciv-450 Tablet 10's Substitute

Medicine Composition:

VALGANCICLOVIR-450MG

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