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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTIVIRALS

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - TEN0497

Author Details

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FAQs

Tenohep-AF Tablet contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.

No, Tenohep-AF Tablet is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.

Tenohep-AF Tablet should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.

A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid drinking alcohol. Consuming alcohol while using Tenohep-AF Tablet may worsen the condition.

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Pregnancy

Caution

Tenohep-AF Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take Tenohep-AF Tablet without the doctor's advice.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Tenohep-AF Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Tenohep-AF Tablet can cause dizziness. If you feel dizzy when taking Tenohep-AF Tablet , do not drive and use any tools or machines.

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Liver

Caution

Consult your doctor before taking Tenohep-AF Tablet if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Kidney

Caution

Consult your doctor before taking Tenohep-AF Tablet if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Unsafe

Should not use Tenohep-AF Tablet in children below 12 years of age.

About Tenohep-AF Tablet

Tenohep-AF Tablet belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Tenohep-AF Tablet contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take Tenohep-AF Tablet as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of Tenohep-AF Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take Tenohep-AF Tablet if you are allergic to Tenohep-AF Tablet or any other contents present in it. Avoid taking Tenohep-AF Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using Tenohep-AF Tablet as it may cause dizziness, affecting your ability to drive or use machines. Should not use Tenohep-AF Tablet for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of Tenohep-AF Tablet

Chronic hepatitis B

Medicinal Benefits Mweb

Medicinal Benefits

Tenohep-AF Tablet ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Tenohep-AF Tablet

  • Diarrhoea
  • Vomiting
  • Feeling sick (nausea)
  • Dizziness
  • Stomach pain
  • Joint pain
  • Feeling bloated
  • Wind (flatulence)
  • Feeling tired

Drug Warnings

You should not take Tenohep-AF Tablet if you are allergic to Tenohep-AF Tablet or any other contents present in it. Avoid taking Tenohep-AF Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using Tenohep-AF Tablet as Tenohep-AF Tablet may cause dizziness, affecting your ability to drive or use machines. Tenohep-AF Tablet is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tenohep-AF Tablet:
Coadministration of Cidofovir and Tenohep-AF Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Tenohep-AF Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tenohep-AF Tablet:
Taking penicillamine and Tenohep-AF Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Penicillamine and Tenohep-AF Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenohep-AF Tablet:
Taking tacrolimus with Tenohep-AF Tablet will have additive effect and may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Tenohep-AF Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tenohep-AF Tablet:
Combining Colistin with Tenohep-AF Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Colistin and Tenohep-AF Tablet, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tenohep-AF Tablet:
Taking Tenohep-AF Tablet with tobramycin can increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenohep-AF Tablet and Tobramycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tenohep-AF Tablet:
Coadministration of Tenohep-AF Tablet with ketorolac may cause kidney problems.

How to manage the interaction:
Although taking Ketorolac and Tenohep-AF Tablet together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, if you experience symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, cramps in your muscles, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tenohep-AF Tablet:
The combined use of Sulfasalazine and Tenohep-AF Tablet can increase the risk or severity of of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and Tenohep-AF Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tenohep-AF Tablet:
Co-administration of Tenohep-AF Tablet may cause kidney problems, and combining it with Cyclophosphamide may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tenohep-AF Tablet if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
How does the drug interact with Tenohep-AF Tablet:
Co-administration of Indomethacin with Tenohep-AF Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Indometacin with Tenohep-AF Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, lack of appetite, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, breathing difficulty, cramping in the muscles, disorientation, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tenohep-AF Tablet:
Combine use of Tenohep-AF Tablet with methotrexate may increase the levels or side effects of Tenohep-AF Tablet.

How to manage the interaction:
Although there is a possible interaction between Tenohep-AF Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TOBRAMYCIN
  • PENTAMIDINE
  • VANCOMYCIN
  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • ADEFOVIR
  • IBUPROFEN

Habit Forming

No

Special Advise

  • If you take Tenohep-AF Tablet , your doctor may regularly monitor liver function, kidney function, and bone density.

Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Tenohep-AF Tablet Substitute

Medicine Composition:

TENOFOVIR ALAFENAMIDE-25MG

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