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Composition :

TOFACITINIB-1MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Medicinal Benefits Mweb

Medicinal Benefits

Novanib-T Oral Solution 100 ml belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Novanib-T Oral Solution 100 ml works by blocking Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. Novanib-T Oral Solution 100 ml is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

About Novanib-T Oral Solution 100 ml

Novanib-T Oral Solution 100 ml belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is an inflammatory condition of the joints, often associated with psoriasis. Ulcerative colitis is an inflammatory disease of the large intestine.
 
Novanib-T Oral Solution 100 ml contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 
 
In some cases, you may experience common side-effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Novanib-T Oral Solution 100 ml if you are pregnant or breastfeeding. Novanib-T Oral Solution 100 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Etanercept with Novanib-T Oral Solution 100 ml can increase the risk of serious infections as well as sometimes may lead to cancers.

How to manage the interaction:
Although there is a possible interaction between Novanib-T Oral Solution 100 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Paclitaxel may increase the risk of infection.

How to manage the interaction:
Although taking Paclitaxel and Novanib-T Oral Solution 100 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Ibrutinib with Novanib-T Oral Solution 100 ml may increase the risk of infection.

How to manage the interaction:
Although taking Novanib-T Oral Solution 100 ml and Ibrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Epirubicin may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Epirubicin with Novanib-T Oral Solution 100 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - make sure to call your doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Oxaliplatin may increase the risk of infection.

How to manage the interaction:
Although taking Oxaliplatin and Novanib-T Oral Solution 100 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Imatinib and Novanib-T Oral Solution 100 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Imatinib can be taken with Novanib-T Oral Solution 100 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Coadministration of Novanib-T Oral Solution 100 ml with Sirolimus may increase the risk or severity of developing infection.

How to manage the interaction:
Although there is a possible interaction between Sirolimus and Novanib-T Oral Solution 100 ml, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Cladribine may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Cladribine and Novanib-T Oral Solution 100 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with leflunomide can increase the risk of infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Novanib-T Oral Solution 100 ml together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Irinotecan may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Novanib-T Oral Solution 100 ml with Irinotecan can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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TOFACITINIB-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TOFACITINIB-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Novanib-T Oral Solution 100 ml can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Novanib-T Oral Solution 100 ml, as it can lead to an interaction.

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

FAQs

Novanib-T Oral Solution 100 ml works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Hypertension/high blood pressure could be a side-effect of Novanib-T Oral Solution 100 ml. Consult your doctor before taking Novanib-T Oral Solution 100 ml if you have high blood pressure or if you are taking anti-hypertensive medicines.

Diarrhoea might be a side-effect of Novanib-T Oral Solution 100 ml. Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Novanib-T Oral Solution 100 ml might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Novanib-T Oral Solution 100 ml if you are trying to become pregnant or if you have any concerns regarding this.

Novanib-T Oral Solution 100 ml affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.

Country of origin

India

Manufacturer/Marketer address

142 Ab, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - NOV0590

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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