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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

INFLIXIMAB-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - INF0228

FAQs

Infimab Injection contains Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.

Infimab Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended for patients with active infections like tuberculosis or abnormal liver enzymes. Infimab Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Infimab Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Infimab Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Infimab Injection passes into human milk. Hence, if you are breastfeeding, inform your doctor before receiving Infimab Injection.

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Driving

Caution

Infimab Injection will be administered in the hospital setting. Hence, driving and operating machines is not recommended.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Infimab Injection. Some patients using $namr have suffered significant liver issues in rare situations. Inform your doctor if you have jaundice (yellowing skin and eyes), dark brown urine discomfort (right-sided abdominal ache, extreme exhaustion (severe fatigue) as a result of a fever.

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Kidney

Caution

If you have kidney impairment, tell your doctor before taking Infimab Injection.

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Children

Safe if prescribed

Infimab Injection is not recommended in children below six years of age as safety and efficacy are not established. In children above six years of age, it will be administered by the pediatrician. Infimab Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and ulcerative colitis.

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Heart

Infimab Injection may increase the risk of heart attack or stroke. Do not use Infimab Injection immediately before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.

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Geriatrics

Caution

Infimab Injection can be used in geriatric patients, but only with caution and close medical supervision due to its long half-life and increased risk of serious side effects.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About Infimab Injection

Infimab Injection belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Infimab Injection consists of Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Infimab Injection may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Infimab Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. 

Infimab Injection may not be suitable for all. Inform your doctor if you are allergic to any of its components. Tell your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system before taking Infimab Injection, as it can worsen your condition. Infimab Injection may cause dizziness, so drive only if you are alert and focused. Infimab Injection should not be given to children under two years of age as safety has not been established. Inform the doctor if you are pregnant or breastfeeding beforehand.

Uses of Infimab Injection

Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Ulcerative colitis.

Medicinal Benefits Mweb

Medicinal Benefits

Infimab Injection consists of Infliximab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. Infimab Injection works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

Directions for Use

Infimab Injection will be administered by a healthcare professional. Do not self-administer.

Side Effects of Infimab Injection

  • Headache
  • Cough
  • Stomach pain
  • Fever
  • Rash
  • Itching
  • Chills
  • Chest pain
  • Shortness of breath

Drug Warnings

Infimab Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes while taking this medicine, as it can worsen these conditions. Lymphomas and other malignancies were reported in children and adolescents treated with Infimab Injection. Hence, it should be used with caution. Do not take live vaccines while being treated with Infimab Injection to prevent any serious consequences. Infimab Injection is not recommended for use in children below six years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Infimab Injection:
Taking Pazopanib and Infimab Injection can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Pazopanib and Infimab Injection, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Infimab Injection:
When Thiotepa is taken with Infimab Injection, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Thiotepa with Infimab Injection can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Infimab Injection:
When Cyclophosphamide is taken with Infimab Injection, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Infimab Injection and Cyclophosphamide together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Infimab Injection:
When Primaquine is taken with Infimab Injection, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infimab Injection with Primaquine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
InfliximabCertolizumab
Severe
How does the drug interact with Infimab Injection:
Combining Infimab Injection with Certolizumab pegol can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infimab Injection and Certolizumab, but it can be taken if prescribed by a doctor. If you experience symptoms like dizziness, severe breathlessness, fever, diarrhea, muscle aches, coughing, nausea, and vomiting it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Infimab Injection:
When Temsirolimus is taken with Infimab Injection, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Infimab Injection and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Infimab Injection:
When Dacarbazine is taken with Infimab Injection, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infimab Injection and Dacarbazine, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Infimab Injection:
Taking ruxolitinib with Infimab Injection it increase the risk or severity of developing infections.

How to manage the interaction:
There may be a possibility of interaction between Ruxolitinib and Infimab Injection, but it can be taken if prescribed by a doctor. However, if you experience symptoms of fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in sputum, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Infimab Injection:
When Vinorelbine and Infimab Injection are taken together, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infimab Injection with Vinorelbine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Infimab Injection:
When Carmustine is taken with Infimab Injection it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infimab Injection and Carmustine, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning while urinating, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TOCILIZUMAB
  • ABATACEPT
  • ANAKINRA
  • CERTOLIZUMAB

Habit Forming

No

Special Advise

  • It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment, though the patient gets a negative tuberculin test.
  • It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Infimab Injection.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

Infimab Injection Substitute

Medicine Composition:

INFLIXIMAB-100MG

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