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  1. Home
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  3. Duonase F Nasal Spray 70 mdi

Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS

Composition :

AZELASTINE-0.1%W/W + FLUTICASONE FUROATE-0.0197%W/W

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIALLERGIC

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DUO0247

Author Details

Written By

Urvashi Bharti

MBBS

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:33 AM IST

We provide you with authentic, trustworthy and relevant information

FAQs

Duonase F Nasal Spray 70 mdi is a combination of two drugs, namely: Fluticasone furoate (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone furoate belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stops the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together, both of them effectively treat allergic symptoms.

No, you are recommended not to use Duonase F Nasal Spray 70 mdi if you have a recent nose operation or have any nose infections as it may lead to nose bleeding and excessive pain in the nose, leading to further worsening of your condition. Consult your doctor and do as advised for the best results.

No, you are not recommended to stop taking Duonase F Nasal Spray 70 mdi without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Duonase F Nasal Spray 70 mdi for as long as your doctor has prescribed it, and if you experience any difficulty while taking Duonase F Nasal Spray 70 mdi, please consult your doctor.

You should avoid taking Duonase F Nasal Spray 70 mdi and consult a doctor before using Duonase F Nasal Spray 70 mdi if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.

Yes, the Duonase F Nasal Spray 70 mdi makes you prone to infections. So as a precautionary measure, please stay away from any person who has chickenpox, measles, or tuberculosis, as they are highly contagious.

No, the Duonase F Nasal Spray 70 mdi is not used to treat asthma attacks. Duonase F Nasal Spray 70 mdi is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Alcohol

Caution

Avoid consumption of alcohol with Duonase F Nasal Spray 70 mdi as it may increase adverse effects. Please consult a doctor before consuming alcohol with Duonase F Nasal Spray 70 mdi.

Pregnancy

Caution

The safety of Duonase F Nasal Spray 70 mdi in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

Breast Feeding

Caution

It is unknown whether Duonase F Nasal Spray 70 mdi is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

Driving

Caution

Duonase F Nasal Spray 70 mdi may cause drowsiness in some people. Therefore, drive only if you are alert after taking Duonase F Nasal Spray 70 mdi.

Liver

Caution

Duonase F Nasal Spray 70 mdi should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Duonase F Nasal Spray 70 mdi.

Kidney

Safe if prescribed

No interaction was found when Duonase F Nasal Spray 70 mdi was taken in a kidney problem. If you have any concerns regarding using Duonase F Nasal Spray 70 mdi in patients with liver problems, please consult a doctor.

Children

Caution

Duonase F Nasal Spray 70 mdi is not recommended for children below six years as the safety and effectiveness were not established.

Reference

  1. https://www.drugs.com/cdi/azelastine-and-fluticasone.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022051lbl.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022203s010s011lbl.pdf

About Duonase F Nasal Spray 70 mdi

Duonase F Nasal Spray 70 mdi belongs to the class of medications called 'antiallergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods, pollen or pet dander. 

Duonase F Nasal Spray 70 mdi combines two drugs: Fluticasone furoate (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone furoate prevents the release of certain chemicals in the body that cause inflammatory reactions. On the other hand, Azelastine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Together, Duonase F Nasal Spray 70 mdi provides relief from allergic symptoms.

Take Duonase F Nasal Spray 70 mdi as advised by your doctor. Your doctor will recommend how often you need to take Duonase F Nasal Spray 70 mdi based on your medical condition. Some people may experience certain common side effects such as headaches, taste changes or nose bleeds. Most of these side effects of Duonase F Nasal Spray 70 mdi do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Duonase F Nasal Spray 70 mdi or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Duonase F Nasal Spray 70 mdi. Duonase F Nasal Spray 70 mdi is not recommended for children below six years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds or increased drowsiness, stop taking Duonase F Nasal Spray 70 mdi and consult a doctor immediately.

Uses of Duonase F Nasal Spray 70 mdi

Allergic symptoms

Medicinal Benefits Mweb

Medicinal Benefits

Duonase F Nasal Spray 70 mdi is a combination of two drugs: Fluticasone furoate and Azelastine, used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose or watery eyes. Fluticasone furoate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Duonase F Nasal Spray 70 mdi relieves allergic symptoms, including seasonal allergies and reduces inflammation of nasal passage.

Directions for Use

Use Duonase F Nasal Spray 70 mdi as advised by your doctor. Check the label for directions before using the Duonase F Nasal Spray 70 mdi.Nasal spray: Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Side Effects of Duonase F Nasal Spray 70 mdi

  • Headache
  • Taste changes
  • Nose bleeds

Drug Warnings

Please inform your doctor if you are allergic to Duonase F Nasal Spray 70 mdi or any other medicines. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Duonase F Nasal Spray 70 mdi and consult a doctor immediately. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Duonase F Nasal Spray 70 mdi. Duonase F Nasal Spray 70 mdi is not recommended for children below six years of age. Avoid contact with people who have infections or who are sick as the Duonase F Nasal Spray 70 mdi may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers, or sores inside the nose, inform your doctor before taking the Duonase F Nasal Spray 70 mdi.

Drug-Drug Interactions

FluticasoneMifepristone
Critical
FluticasoneAtazanavir
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Duonase F Nasal Spray 70 mdi with Mifepristone may make Duonase F Nasal Spray 70 mdi less effective as a therapy.

How to manage the interaction:
Taking Duonase F Nasal Spray 70 mdi with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
FluticasoneAtazanavir
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Atazanavir and Duonase F Nasal Spray 70 mdi may significantly increase the absorption of Duonase F Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Co-administration of Atazanavir and Duonase F Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneBoceprevir
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Boceprevir with Duonase F Nasal Spray 70 mdi may significantly increase the absorption of Duonase F Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Co-administration of Boceprevir and Duonase F Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneTroleandomycin
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Troleandomycin may significantly increase the absorption of Duonase F Nasal Spray 70 mdi and tend to increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Duonase F Nasal Spray 70 mdi and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
FluticasoneDinutuximab
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Dinutuximab and Duonase F Nasal Spray 70 mdi may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Duonase F Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneKetoconazole
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Ketoconazole and Duonase F Nasal Spray 70 mdi may significantly increase the absorption of Duonase F Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
If you are supposed to take Duonase F Nasal Spray 70 mdi and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneNefazodone
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Nefazodone may significantly increase the absorption of Duonase F Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Co-administration of Duonase F Nasal Spray 70 mdi with Nefazodone can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
FluticasonePosaconazole
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Duonase F Nasal Spray 70 mdi with posaconazole may increase the level of Duonase F Nasal Spray 70 mdi in the blood and increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Duonase F Nasal Spray 70 mdi and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
Co-administration of Mibefradil may significantly increase the absorption of Duonase F Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Taking Duonase F Nasal Spray 70 mdi with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneConivaptan
Severe
How does the drug interact with Duonase F Nasal Spray 70 mdi:
When Conivaptan is taken with Duonase F Nasal Spray 70 mdi, it can make Conivaptan break down faster in the body.

How to manage the interaction:
Co-administration of Conivaptan and Duonase F Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • ESCITALOPRAM
  • PREGABALIN
  • RITONAVIR
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ITRACONAZOLE
  • CETIRIZINE

Habit Forming

No

Special Advise

  • Certain blood tests are recommended while taking Duonase F Nasal Spray 70 mdi to monitor serum cortisol levels, as Duonase F Nasal Spray 70 mdi may increase these levels.
  • Also, avoid smoking as it might worsen your symptoms, so avoid tobacco intake.

Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation, and swelling in nasal passages.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
  • The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress.
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

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