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Impentin Injection Substitute

Medicine Composition:

CILASTATIN-500MG + IMIPENEM-500MG

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All Substitutes & Brand Comparisons

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When Should You Consider Switching from Impentin Injection?

Patients may explore substitutes in the following scenarios:

  • High monthly cost of Impentin Injection
  • Non-availability in local pharmacies
  • Generic recommendation by a doctor
  • Side effects or better tolerability with alternatives

What to Know Before Switching

Before you switch from Impentin Injection to another medicine, here are some important points to keep in mind:

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Same salt, different brands:

Most substitutes contain the same active ingredient - CILASTATIN-500MG + IMIPENEM-500MG, but the fillers, coating, or manufacturing quality may vary slightly.

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Consult your doctor first:

Even if the salt is the same, your doctor can confirm if the substitute is right for your condition, dosage, and health history.

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Watch out for allergies or reactions:

Some people may react differently to certain brands due to inactive ingredients. If you notice any side effects, inform your doctor immediately.

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Price ≠ effectiveness:

A lower-priced substitute doesn't mean it's less effective. Many generic medicines work just as well as branded ones.

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Check the dosage form and strength:

Always match the substitute’s strength (e.g., 5mg, 10mg) and form (tablet, capsule, syrup) with what your doctor prescribed.

Uses

Severe bacterial infections

Medicinal Benefits

Impentin Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Impentin Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. Impentin Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Impentin Injection helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

FAQs

The substitutes of Impentin Injection contain the same active salt(s) - CILASTATIN-500MG + IMIPENEM-500MG. However, they may differ in price, manufacturing quality, and inactive ingredients. Speak to your doctor to find a suitable option.

Switching to a generic substitute medicine in the place of Impentin Injection is often possible if it has the same salt, strength, and dosage form. But always check with your doctor before making any changes to your medication.

Generics versions of Impentin Injection are typically more affordable because they don’t include the original brand's research, development, and marketing costs. They contain the same active ingredient and are approved for safety and effectiveness.

Most people don’t notice any difference. However, some may react to different fillers or coatings. If you notice any unusual symptoms after switching, consult your doctor.

Make sure the new medicine has the same active salt, strength, dosage form. Always confirm the change with your doctor or pharmacist.

Substitutes of Impentin Injection meet the same safety and efficacy standards as Impentin Injection, but small differences in absorption or formulation can exist. A doctor can help you choose the right one for your needs.

Yes. Substitutes of Impentin Injection may vary in color, size, or shape due to differences in manufacturing and branding, but this does not affect how they work.

Yes, it’s generally safe to switch between multiple substitutes of Impentin Injection if they have the same salt and strength. However, always inform your doctor so they can monitor how your body responds.

Yes, many people safely use substitutes of Impentin Injection for long-term treatment. Just ensure it’s done under medical supervision.

If your symptoms stay under control or lab results remain stable, the substitute for Impentin Injection is likely working well. Regular follow-ups with your doctor are important.

Absolutely. Even with the same salt, small differences can affect how your body responds when switching from Impentin Injection to its substitute. Always consult your doctor before switching.

Impentin Injection is a combination of two drugs, namely: Cilastatin and Imipenem. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Impentin Injection helps to treat bacterial infections.

Diarrhoea might be a side-effect of Impentin Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.

Concomitant administration of Probenecid (used to treat gout and hyperuricemia) along with Impentin Injection is not recommended as it might result in an increase of plasma levels and half-life of Imipenem.

Ganciclovir (anti-viral) should not be co-administered along with Impentin Injection unless benefits outweigh the risks as generalised seizures have been reported when taken together.

Impentin Injection may cause changes in urine colour and amount of urine. Do not worry and consult your doctor if you have any concerns regarding this.

Impentin Injection may rarely cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

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